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PubMed · 471371

hPL: physiologic and pathophysiologic observations.

F J Zlatnik·M W Varner·K S Hauser·S S Lee
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Abstract

Serum human placental lactogen (hPL) levels were studied in 806 women in late pregnancy. The hPL levels were positively correlated with birth weight but were unrelated to maternal age, parity, socioeconomic status, or the sex of the newborn. The hPL levels peaked at 37 weeks' gestation and then declined moderately. An individual's hPL levels in late pregnancy are quite constant week to week. Patients with severe chronic hypertension have low hPL values; those carrying twins have high values.

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Birth WeightFemaleGestational AgeHumansInfant, NewbornMalePlacental LactogenPregnancyPregnancy ComplicationsPregnancy Trimester, ThirdPregnancy, MultipleJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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F J Zlatnik, M W Varner, K S Hauser, S S Lee. 1979. hPL: physiologic and pathophysiologic observations.. https://pubmed.ncbi.nlm.nih.gov/471371/

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Prediction of light-for-gestational age at delivery in twin pregnancies: an evaluation of fetal weight deviation and growth discordance measured by ultrasound.

The purpose of this retrospective study was to evaluate and discuss different ultrasound methods widely used, among other things, as predictors for light-for-gestational age (LGA) in twin pregnancies. The methods evaluated and compared as predictors for LGA at birth were: (1) Difference between twins in biparietal diameter; (2) difference in abdominal diameter; (3) the percentage difference in estimated fetal weight between twins; and (4) estimation of the weight deviation from the expected weight during pregnancy. The study comprised 66 twin pregnancies, examined by ultrasound scanning less than 15 days before delivery. Using Relative Operating Characteristic curves (ROC curves) estimated fetal weight deviation was the most sensitive and specific of the methods. It is stressed that fetal discordance is not the appropriate predictor of LGA at birth in twin pregnancies.

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