Improved method for obtaining streptomycin-dependent mutants from Pasteurella multocida and Pasteurella haemolytica, using N-methyl-N'-nitro-N-nitrosoguanidine.

M M Chengappa; G R Carter

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PubMed · 475104

Improved method for obtaining streptomycin-dependent mutants from Pasteurella multocida and Pasteurella haemolytica, using N-methyl-N'-nitro-N-nitrosoguanidine.

M M Chengappa·G R Carter

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Abstract

N-Methyl-N'-nitro-N-nitrosoguanidine was used in a modified and improved procedure to obtain streptomycin-dependent mutants of type A Pasteurella multocida and type 1 Pasteurella haemolytica. The relative virulence of these mutants was determined by mouse inoculation with and without streptomycin.

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Animals Methylnitronitrosoguanidine Mice Mutation Pasteurella Streptomycin Temperature Virulence Journal Article

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M M Chengappa, G R Carter. 1979. Improved method for obtaining streptomycin-dependent mutants from Pasteurella multocida and Pasteurella haemolytica, using N-methyl-N'-nitro-N-nitrosoguanidine.. https://pubmed.ncbi.nlm.nih.gov/475104/

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