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Plasmenylethanolamine: growth factor for cholesterol-reducing Eubacterium.

Abstract

A plasmalogen, plasmenylethanolamine, is required for in vitro growth of strains of Eubacterium which convert cholesterol to coprostanol. Plasmenylethanolamine was isolated from calf brain by selective saponification of lipid fractions separated by thin-layer or column chromatography. Cholesterol-containing thioglycolate broth plus purified plasmenylethanolamine or its 2-lyso derivative supported growth of Eubacterium ATCC 21408 and a cholesterol-reducing Eubacterium isolated from baboon feces. Plasmenylethanolamine obtained from commercial sources also supported growth of these organisms, but none of a number of other pure lipids would support growth. Metabolism of the alkenyl ether group of plasmenylethanolamine occurred during growth.

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BibTeXRIS

G E Mott, A W Brinkley. 1979. Plasmenylethanolamine: growth factor for cholesterol-reducing Eubacterium.. https://doi.org/10.1128/jb.139.3.755-760.1979

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