PubMed · 4795267
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M Kitamura. 1973. [What is the normal value?].. https://pubmed.ncbi.nlm.nih.gov/4795267/
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To evaluate a new reflectance photometer (Accusport) for blood lactate determination, a prospective non-interventional study was performed on blood obtained from the umbilical cord artery immediately after delivery of the baby in 109 consecutive women. For each sample, the results of cord arterial blood lactate values measured with the reflectance photometer were compared with those obtained using a reference method in the laboratory. The values obtained using Accusport were comparable in accuracy with those obtained using a laboratory reference method (Ektachem 9501RC). The instrument provides a simple and reliable method for determining cord arterial blood lactate levels in a small blood sample.
Present techniques for the detection of gunshot residue rely primarily metallic primer components such as lead, barium and antimony. With the advent of reformulated primers that reduce or eliminate these elements, new methods for the detection of organic residue compounds will be needed. Micellar electrokinetic capillary electrophoresis (MECE) is one technique that has been successfully applied to the analysis of these smokeless powder residue compounds. Protocols for the recovery of the organic residue components under a variety of sampling conditions were evaluated and improved for MECE analysis. The collection of residue samples where external contaminants such as grease or blood were present on the residue substrate were investigated using both tape lifts and solvent swab protocols. In addition, residue component recovery using supercritical fluid extraction techniques was preliminarily evaluated for samples contaminated with blood.
The Total Testing Process (TTP) refers to the sequence of 11 steps of laboratory testing, beginning with a clinical question prompted by the patient-clinician encounter and concluding with the impact of the test result on patient care. TTP when applied to therapeutic drug monitoring (TDM) emphasizes that TDM must be considered a process involving a series of steps and interrelated activities and not viewed simply as a numerical value for a serum drug concentration. TTP is also an ideal format for organizing and identifying the system-related and patient-centered variables used in outcomes assessment of TDM, as well as providing a template for collecting the cost data needed for economic analyses. Examples are provided for improving application of TDM by practitioners, clinical laboratories, and educators.