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Codon recognition by enzymatically mischarged valine transfer ribonucleic acid.

D Grunberger·I B Weinstein·K B Jacobson
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Abstract

Direct evidence for the adaptor hypothesis has been obtained by examining the codon recognition of a purified Escherichia coli valine transfer ribonucleic acid which was enzymatically mischarged with phenylalanine labeled with carbn-14 by reaction with purified phenylalanyl-transfer ribonucleic acid synthetase from Neurospora crassa. The mischarged transfer ribonucleic acid recognized the valine codons but failed to recognize the phenylalanine codon when tested in trinucleotide-directed ribosomal binding assay.

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Bacterial ProteinsCarbon IsotopesEscherichia coliGenetic CodeNeurosporaPhenylalanineRNA, BacterialRNA, TransferValineJournal Article

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D Grunberger, I B Weinstein, K B Jacobson. 1969-12-26. Codon recognition by enzymatically mischarged valine transfer ribonucleic acid.. https://doi.org/10.1126/science.166.3913.1635

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