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Herpes simplex virus type 1 replication in a gingival cell line.

R D Fletcher·J Guggenheimer·D Sumney·D Platt
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Abstract

Propagation of herpes simplex virus type 1 (HSV-1) in gingival cells is advantageous since these cells are more definitive than HeLa cells in demonstrating viral-induced cytopathic effects and are easily and economically maintained in the laboratory. They also provide a potential medium for studying oral tissue reactions to HSV-1 infection. HSV-1-induced cytopathic effects are clearly characterized following inoculation with virus from standard laboratory cultures and human infections.

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Cell LineCell NucleusChromatinChromosomesCytoplasmDesmosomesGingivaHumansMitosisSimplexvirusStaining and LabelingVacuolesVirus CultivationVirus ReplicationJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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R D Fletcher, J Guggenheimer, D Sumney, D Platt. Herpes simplex virus type 1 replication in a gingival cell line.. https://doi.org/10.1177/00220345750540030401

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