Water, protein folding, and the genetic code.

R V Wolfenden; P M Cullis; C C Southgate

doi:10.1126/science.493962

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PubMed · 493962

Water, protein folding, and the genetic code.

R V Wolfenden·P M Cullis·C C Southgate

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Abstract

The absolute affinities of amino acid side chains for solvent water closely match their relative distributions between the surface and the interior of native proteins and are associated with a remarkable bias in the genetic code.

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Amino Acids Genetic Code Mutation Protein Conformation Solubility Thermodynamics Water Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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R V Wolfenden, P M Cullis, C C Southgate. 1979-11-02. Water, protein folding, and the genetic code.. https://doi.org/10.1126/science.493962

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