PubMed · 5011565
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
G Zipser. 1972-01-22. Amniotic fluid embolism.. https://pubmed.ncbi.nlm.nih.gov/5011565/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
Since endothelin is a potent vasoconstrictor and bronchoconstrictor, endothelin-1 expression in the lung was investigated using immunohistological techniques in two cases of amniotic fluid embolism. Intense expression of endothelin-1 was observed in amniotic squames while weaker staining was seen in alveolar epithelium, bronchiolar epithelium and intraalveolar macrophages and focally in vascular endothelium. Endothelin-1 may play a role in the early and transient haemodynamic alteration of pulmonary hypertension in amniotic fluid embolism.
Explore the source record for details and available documents.
AFE, although rare, remains a significant cause of maternal mortality. Even with improvements in supportive care, the prognosis remains poor for mother and fetus. The guidelines presented may help the physician to recognize this condition when it occurs and give some direction for therapy.