PubMed · 5071757
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J Albrecht, H Rheinfurth. 1972-09-22. [Bacteriological urine diagnostics].. https://pubmed.ncbi.nlm.nih.gov/5071757/
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Urinary tract infection is an old problem that continues to present new challenges. The purpose of this special edition is to pull together new basic scientific information regarding the pathogenesis of infection and to review the state of the art in the evaluation and treatment of urinary tract infection in some of the more complex or challenging clinical settings. The goal has been more than a summarization of current knowledge; the intent has been to highlight areas of uncertainty, thereby emphasizing the need for further investigation. Herein we briefly mention four clinical settings for urinary tract infection that, in our opinion, present important new or evolving challenges and are particularly fertile areas for further work.
OBJECTIVE: To compare the accuracy of cultures of urine obtained by clean-catch urine (CCU) collection and suprapubic aspiration (SPA) in infants. DESIGN: Prospective case series undertaken in a pediatric teaching hospital and associated neonatal unit. Fifty-eight paired urine cultures (CCU collection and SPA) were obtained from 49 infants with suspected urinary tract infection. The primary outcome measure was the presence or absence of significant bacteriuria on both CCU collection and SPA; secondary outcome measures were the success of SPA with ultrasound guidance compared with aspiration without ultrasound guidance. Statistical analysis was done by using a chi(2) test. RESULTS: A false-positive rate of 5% and a false-negative rate of 12% were recorded. Sensitivity was 88.9% (95% CI 65.3-98.6), and specificity was 95.0% (95 CI% 83.1-99. 4). Ultrasound-assisted SPA was successful in 26 of 28 patients (93%) and in 13 of 21 patients (62%) when SPA was performed without ultrasound (chi(2) = 7.08, P =.008). CONCLUSIONS: We conclude that there is a good association in results of culture of urine obtained by CCU collection and SPA and would encourage the use of the CCU technique.
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