Methamphetamine-induced insulin release.

E M McMahon; D K Andersen; J M Feldman; S M Schanberg

doi:10.1126/science.174.4004.66

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PubMed · 5120870

Methamphetamine-induced insulin release.

E M McMahon·D K Andersen·J M Feldman·S M Schanberg

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Abstract

Administration of methamphetamine or amphetamine to rats and mice produces a rapid increase in the level of immunoassayable plasma insulin not attributable to hyperglycemia. While in the mouse this release of insulin is followed consistently by a profound hypoglycemia, in the rat this response is variable. Studies in vitro demonstrate that insulin is released by a direct effect of methamphetamine on the pancreas.

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Animals Blood Glucose Injections, Intraperitoneal Injections, Intravenous Insulin Insulin Secretion Male Methamphetamine Mice Pancreas Radioimmunoassay Rats Time Factors Journal Article

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E M McMahon, D K Andersen, J M Feldman, S M Schanberg. 1971-10-01. Methamphetamine-induced insulin release.. https://doi.org/10.1126/science.174.4004.66

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