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A rapid, sensitive method for quantifying enflurane in whole blood.

M S Miller·A J Gandolfi
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Abstract

Thermal conductively detection (TCD) in conjunction with gas-liquid chromatography was employed for the analysis of enflurane in n-heptane extracts of whole blood. Enflurane was estimated to be 98 per cent extracted from whole blood by n-heptane. Analysis of enflurane standards ranging in concentration from 4.1 to 813 muM demonstrated linearity, with a correlation coefficient of 0.9999. As little as 8 muM enflurane may be detected in whole blood. TCD gas-liquid chromatography is a rapid and sensitive method for quantifying enflurane in whole blood.

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Chromatography, GasEnfluraneHeptanesHumansThermal ConductivityTime FactorsJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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M S Miller, A J Gandolfi. 1979. A rapid, sensitive method for quantifying enflurane in whole blood.. https://doi.org/10.1097/00000542-197912000-00012

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