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Behavior in chimeric mice combining differently behaving strains.

M N Nesbitt·M A Spence·K Butler
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Abstract

A/J and C57BL/6J mice behave differently in tests for alcohol preference, open-field activity, defecation in the open field, cricket attacking, and rope climbing. Chimeric mice, i.e., mice containing both A/J cells and C57BL/6J cells, were constructed and tested for these behaviors. Patterns of behavior among A/J in equilibrium with C57BL/6J chimeras are such as to suggest that none of these behavior differences is controlled by a single cell or clone and that the same cell population that gives rise to the strain difference in alcohol preference also gives rise to the differences in open-field activity and defecation, while separate cell populations control cricket killing and rope climbing.

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Alcohol DrinkingAnimalsBehavior, AnimalChimeraMiceMice, Inbred AMice, Inbred C57BLPredatory BehaviorJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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M N Nesbitt, M A Spence, K Butler. 1979. Behavior in chimeric mice combining differently behaving strains.. https://doi.org/10.1007/bf01068206

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