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A surface antigen marker for human monocytes.

M F Greaves·J A Falk·R E Falk
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Abstract

Antisera have been raised in rabbits aginst human peritoneal macrophages. After absorption with tonsil cells the sera reacted, by direct and indirect immunfluorescence, with phagocytic mononuclear cells from a variety of tissues and, in addition, stained a small population of nonphagocytic non-T, non-B mononuclear cells present in blood, spleen, and marrow but absent or very rare in tonsil and thymus. The antisera may define a human monocyte-macrophage cell surface differentiation antigen (HuMA) and can be used to deplete or enrich reactive cell population.

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AnimalsAntigen-Antibody ReactionsAntigensBone MarrowCell MembraneCytotoxicity Tests, ImmunologicEpitopesHumansImmune SeraLymphocytesMiceMonocytesPalatine TonsilPhagocytosisRabbitsSpecies SpecificitySpleenThymus GlandJournal Article

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M F Greaves, J A Falk, R E Falk. 1975. A surface antigen marker for human monocytes.. https://doi.org/10.1111/j.1365-3083.1975.tb02661.x

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