PubMed · 5267517
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
J M Iglesias. [Calcium hydroxide therapy].. https://pubmed.ncbi.nlm.nih.gov/5267517/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
This report presents a case of a completely intrusive luxation of a mature permanent central incisor in a 10-yr-old boy. The intruded tooth was repositioned by using surgical extrusion and stabilization with interdental sutures. Endodontic treatment was performed with calcium hydroxide paste as the intracanal medication and a calcium hydroxide-based root canal sealer. This treatment mode was observed at 18 months and was successful at that time.
OBJECTIVE: Calcium hydroxide is a common intracanal medicament. The powder can be mixed with different vehicles for placement in canals. This study examines pH changes in dentin with 2 different calcium hydroxide preparations. STUDY DESIGN: The combinations used were calcium hydroxide + distilled water and calcium hydroxide + glycerin (1/7 distilled water). One hundred forty extracted teeth with single canals were used. pH changes in dentin after the intracanal placement of these combinations were evaluated at different dentin thicknesses by measuring the pH of the external environment. RESULTS: For all dentin thicknesses and at all time periods, the calcium hydroxide + glycerin combination showed significantly higher pH values than the calcium hydroxide + distilled water combination. CONCLUSIONS: Considering pH elevations, we propose the use of a calcium hydroxide + glycerin combination.
The response of the dental pulp to calcium hydroxide has been well described but the process of pulpal repair leading to dentinal bridge formation appears complex and the mechanisms remain incompletely understood. Through the precise regulation of the free calcium ion in the cytosol, cells have been able to utilize anions such as phosphates for a wide range of activities such as energy production (oxidative phosphorylation). As anions are abundant in the cytosol, intracellular levels of calcium ions are kept low, several orders of magnitude less than that of the surrounding extracellular matrix. Consequently, cells are able to use calcium ions for the regulation of many cellular events. The binding of extracellular molecules such as cytokines, hormones or antibodies, with receptors on the plasma membrane may result in short- or long-term modifications to cellular metabolism, including the mechanisms of intracellular calcium homeostasis. Cell survival depends upon the ability to adapt to changes in the cell's micro-environment. Adaptation in turn results in altered cellular activity that may be interpreted as showing that the cell has become more or less specialised. In some instances this may include the resumption of mitotic activity. If the rate or magnitude of change exceeds a cell's adaptive capacity, the cell dies. Responses of cells to alterations in their environment are reviewed as they may provide an explanation for the success of calcium hydroxide in facilitating pulpal repair and the differentiation of odontoblasts.