Hydrolysis of chylomicron triacylglycerol by endothelium-bound lipoprotein lipase. Effect of decreased apoprotein C-II/C-III ratio.

T J Kotlar; J Borensztajn

doi:10.1042/bj1830171

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Hydrolysis of chylomicron triacylglycerol by endothelium-bound lipoprotein lipase. Effect of decreased apoprotein C-II/C-III ratio.

T J Kotlar·J Borensztajn

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Abstract

Chylomicrons with a decreased ratio of C-II/C-III apoproteins on their surface produced by the addition of apoproteins C-III-0 or C-III-3 to intact rat lymph chylomicrons. These chylomicrons inhibited the activity of soluble lipoprotein lipase in vitro, but had no effect on the activity of the endothelium-bound enzyme in the perfused heart.

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Animals Apoproteins Chylomicrons Electrophoresis, Polyacrylamide Gel Endothelium Hydrolysis Lipoprotein Lipase Male Myocardium Protein Binding Rats Triglycerides Journal Article Research Support, U.S. Gov't, P.H.S.

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T J Kotlar, J Borensztajn. 1979-10-01. Hydrolysis of chylomicron triacylglycerol by endothelium-bound lipoprotein lipase. Effect of decreased apoprotein C-II/C-III ratio.. https://doi.org/10.1042/bj1830171

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