Lymphokine-induced changes in macrophage transmembrane electrical potentials.

R C Niemtzow; J L Rossio; M H Olson; L Gauci; J C Daniels; B Serrou

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PubMed · 543929

Lymphokine-induced changes in macrophage transmembrane electrical potentials.

R C Niemtzow·J L Rossio·M H Olson·L Gauci·J C Daniels·B Serrou

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Abstract

Intracellular electrical potentials have been measured in nonactivated and immunologically-activated macrophages obtained from the peritoneal cavities of mice. Normal macrophage potentials were established and found to become significantly more electronegative after in vitro exposure for 10 minutes to a lymphokine-containing supernatant which induced macrophage activation. This approach may reflect very early concomitants of such activation and is also useful in the study of other immunologic systems.

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Animals Cell Membrane Lymphokines Macrophages Membrane Potentials Mice Mice, Inbred Strains Journal Article

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R C Niemtzow, J L Rossio, M H Olson, L Gauci, J C Daniels, B Serrou. 1979. Lymphokine-induced changes in macrophage transmembrane electrical potentials.. https://pubmed.ncbi.nlm.nih.gov/543929/

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