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PubMed · 5450369

Hemoglobin interaction: modification of solid phase composition in the sickling phenomenon.

J F Bertles·R Rabinowitz·J Döbler
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Abstract

Direct analyses of solid phase formed by deoxygenating solutions of sickle-cell hemoglobin (Hb S) in the presence of certain other hemoglobin species show that hemoglobins A and C can participate in the filamentous fine structure characteristic of the sickling phenomenon. In contrast, fetal hemoglobin (Hb F) is nearly completely excluded.

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Anemia, Sickle CellBlood ViscosityCell-Free SystemChemical PhenomenaChemistry, PhysicalErythrocytesFetal HemoglobinHemoglobin CHemoglobin C DiseaseHemoglobinsHemoglobins, AbnormalHumansMicroscopy, ElectronOxygenPeptidesJournal Article

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J F Bertles, R Rabinowitz, J Döbler. 1970-07-24. Hemoglobin interaction: modification of solid phase composition in the sickling phenomenon.. https://doi.org/10.1126/science.169.3943.375

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