PubMed · 550227
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A Cáceres, A Ponce López, C L Fletes, S Ortiź. [Toxoplasmic chorioretinitis; various data for its study].. https://pubmed.ncbi.nlm.nih.gov/550227/
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PURPOSE: To determine choroidal involvement in presumed tuberculous posterior uveitis by examining indocyanine green angiographic features. METHODS: Indocyanine green angiography was performed according to a standard uveitis angiographic protocol in eight consecutive patients (15 eyes) with presumed posterior tuberculous uveitis. RESULTS: In 100% of the 15 examined eyes, indocyanine green angiography disclosed choroidal lesions that were subclinical, not detected by fundus examination or fluorescein angiography, in six (40%) of 15 eyes. Findings were classified into four main angiographic signs: (1) irregularly distributed, hypofluorescent areas in the early and intermediate phases of angiography that either became isofluorescent (type 1 hypofluorescence) or remained hypofluorescent (type 2 hypofluorescence) in the late phase; (2) numerous, small, focal, hyperfluorescent spots; (3) choroidal vessels that appeared fuzzy in the intermediate phase because of leakage, leading in the late phase to (4) diffuse choroidal hyperfluorescence. Type 1 hypofluorescent lesions, fuzzy choroidal vessels, and diffuse choroidal hyperfluorescence tended to regress after the initiation of antituberculous and corticosteroid treatment. Focal hyperfluorescence tended to be associated with longstanding disease. CONCLUSIONS: Indocyanine green angiography was useful in assessing and quantifying the as yet unknown extent of choroidal involvement in tuberculous posterior uveitis. Its characteristic appearance may be a valuable contribution to the diagnosis and monitoring of treatment response.
PURPOSE: To report the appearance of birdshot retinochoroidopathy in a patient with myelodysplasia syndrome. METHOD: Case report of a healthy 62-year-old woman who was fortuitously noted to have multiple atrophic spots in the posterior choroid and retina of each eye. RESULT: Subsequent medical evaluation included a blood cell count that disclosed pancytopenia, with a diagnosis of myelodysplasia made on bone marrow examination. CONCLUSION: An autoimmune response associated with the underlying myelodysplasia may be responsible for the appearance of atrophic retinal and choroidal lesions resembling birdshot retinochoroidopathy.
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