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PubMed · 57194

Complement - fixation in the interaction of normal rabbit gamma G' globulin and its Fab' fragment.

L M Bartova·N E Shmeleva·I A Tarkhanova
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Abstract

Complement consumption induced by Fab' fragments of rabbit IgG, irrespectively of their state of aggregation, requires the presence of homologous rabbit IgG. Up to a certain concentration of Fab' fragment, the amount of complement fixed is a linear function of the Fab' fragment dose, but further raising of the Fab'-fragment concentration does not result in complete complement consumption in the sample. The interaction between Fab' fragment and IgG is not strictly species specific.

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AnimalsComplement Fixation TestsGuinea PigsImmunoglobulin Fab FragmentsRabbitsSpecies Specificitygamma-GlobulinsJournal Article

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L M Bartova, N E Shmeleva, I A Tarkhanova. 1976. Complement - fixation in the interaction of normal rabbit gamma G' globulin and its Fab' fragment.. https://pubmed.ncbi.nlm.nih.gov/57194/

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