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Leukotactic factor produced by sensitized lymphocytes.

P A Ward·H G Remold·J R David
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Abstract

Lymph node lymphocytes obtained from guinea pigs exhibiting delayed hypersensitivity are stimulated in vitro by specific antigen to produce a soluble factor that is chemotactic in vitro for mononuclear macrophages. The material is nondialyzable, relatively heat stable, and elutes from Sephadex G-100 in the fraction containing molecules smaller than immunoglobulins.

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AnimalsAntigensCell BiologyChemotaxisChromatography, GelDialysisGuinea PigsHot TemperatureHypersensitivity, DelayedLeukocytesLymphocytesRabbitsJournal Article

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P A Ward, H G Remold, J R David. 1969-03-07. Leukotactic factor produced by sensitized lymphocytes.. https://doi.org/10.1126/science.163.3871.1079

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