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PubMed · 5778011

Encephalitogenic protein: structure.

R F Kibler·R Shapira·S McKneally·J Jenkins·P Selden·F Chou
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Abstract

Amino acid sequences of encephalitogenic proteins from bovine cord and rabbit brain are reported. The bovine protein contains 45 residues. The rabbit protein is identical except for two isopolar substitutions, a dipeptide and amino acid deletion. Analysis of this protein and a 140-residue myelin basic protein indicates that the smaller protein is a portion of the larger encephalitogen. The larger myelin protein contains at least two encephalitogenic sites.

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Amino Acid SequenceAnimalsBrain ChemistryCattleChromatography, GelChymotrypsinEncephalomyelitis, Autoimmune, ExperimentalMyelin SheathNerve Tissue ProteinsNitrobenzenesPeptidesRabbitsSpinal CordTrypsinJournal Article

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R F Kibler, R Shapira, S McKneally, J Jenkins, P Selden, F Chou. 1969-05-02. Encephalitogenic protein: structure.. https://doi.org/10.1126/science.164.3879.577

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