PubMed · 5898504
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Bergeret, Dany, Vendryes. 1965. [Digestive diseases].. https://pubmed.ncbi.nlm.nih.gov/5898504/
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Well-known mineral baths in Bulgaria, 'Hissarya', are described. Their existence dates back more than 25 centuries. 'Hissarya' is an Arabic word meaning 'siege of a castle'. Remains of castle walls are the symbol of 'Hissarya' today. Every year more than 100,000 patients from Bulgaria and other countries visit 'Hissarya'. From the time of the Thracians and the Roman Empire until now renal stones have been successfully treated by drinking the mineral water and by taking baths. The Roman Emperor Septimius Severus (193-211) visited 'Hissarya' every spring to treat his renal disease.
BACKGROUND: Balneology and spa therapy, although not accepted as well-established treatment modalities in dermatology, are used throughout the world. The therapeutic properties for skin and rheumatic diseases of the Dead Sea area may be attributed to unique climatic characteristics and unique natural resources. The mechanisms by which a broad spectrum of diseases are alleviated by spa therapy may involve mechanical, thermal, and chemical effects. OBJECTIVE: To review and discuss various spa therapy modalities, used at the Dead Sea area for a wide spectrum of skin diseases. CONCLUSIONS: Existing evidence indicates the therapeutic potential of Dead Sea spa therapy modalities for psoriasis and psoriatic arthritis. A beneficial effect is hinted at for other skin diseases, but the absence of relevant methodological and clinical information precludes the drawing of any scientific conclusions. It is essential to establish therapeutic guidelines to determine the optimal treatment modality for each disease, and the optimal protocol of each treatment component, adjusted individually for each patient, with respect to remission and long-term adverse effects.
A 56-year-old female patient with generalized granuloma anulare was treated with bath-PUVA therapy with 8-methoxypsoralen. Her diabetes mellitus renal insufficiency excluded oral photochemotherapy. A series of 30 treatments resulted in complete disappearance of the lesions on the trunk and neck and significant improvement of those on the limbs. No side-effects were observed. Bath-PUVA therapy seems to have positive effects not only on epidermal, but also on dermal processes.