Structure-activity studies on hallucinogenic amphetamines using molecular connectivity.

L B Kier; L H Hall

doi:10.1021/jm00222a019

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Structure-activity studies on hallucinogenic amphetamines using molecular connectivity.

L B Kier·L H Hall

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Abstract

A series of ring-substituted hallucinogenic amphetamines has been analyzed using molecular connectivity. A correlating equation has been found between potency and connectivity terms. The equation permits an interpretation of SAR. The equation is capable of predicting potency for amphetamines not in the list and mescalines and tryptamines.

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Amphetamines Chemical Phenomena Chemistry, Physical Hallucinogens Models, Chemical Structure-Activity Relationship Journal Article

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L B Kier, L H Hall. 1977. Structure-activity studies on hallucinogenic amphetamines using molecular connectivity.. https://doi.org/10.1021/jm00222a019

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