PubMed · 5938861
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
R K Brown, K P Clearkin, K Nakachi, C O Burdick. 1966-07-21. Elastofibroma dorsi.. https://doi.org/10.1056/nejm196607212750307
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
STUDY DESIGN: A retrospective study was performed of 182 revisions on failed back surgery syndrome from the years 1965 to 1990. OBJECTIVE: To analyze the reasons for failure of primary discectomy, the outcome of the revisions, and factors that influenced those outcomes. SUMMARY OF BACKGROUND DATA: The reported reintervention rates after lumbar discectomy range from 5% to 33% depending on the type of surgical procedure. The authors' former investigations reported a revision rate of 10.8% in evaluating 1500 lumbar discectomies. METHODS: Because the documentation was standardized, detailed data of all patients were available. To gain further information concerning the long-term results a questionnaire was used. Computer processing and statistical tests were performed. RESULTS: One hundred eighty-two revisions were performed on 136 patients. Forty-four patients (34%) were revised multiple times. Generally, recurrent or uninfluenced sciatic pain and neurologic deficiency or lumbar instability led to reintervention. Recurrent lumbar disc herniation mainly was found at the first reintervention. In multiple revision patients the rate of epidural fibrosis and instability increased to greater than 60%. In 80% of the patients the results were satisfactory in short-term evaluation, decreasing to 22% in long-term follow up (2-27 years). CONCLUSIONS: Laminectomy performed in primary surgery could be detected as the only factor leading to a higher rate of revisions. A trend toward poor results after recurrent disc surgery seems to be fateful because of the development of epidural fibrosis and instability. In severe discotomy syndrome, a spinal fusion seems to be more successful than multiple fibrinolyses.
Explore the source record for details and available documents.
Failed back surgery syndrome (FBSS) is the presence of persistent, disabling pain in the hip, thigh, leg, or lower back of a patient who has undergone a laminectomy or discectomy. Some degree of FBSS is found in approximately 15% of such patients. There may be a direct relationship between the extent of pathology found during the initial surgical procedure and the probability that FBSS will develop. Although FBSS is usually due to improper diagnosis and surgery, another important cause is peridural fibrosis. Part of the answer may have to do with neuromechanics. In a healthy person, pain associated with dural and nerve root movement does not typically occur when performing activities of daily living. In contrast, in a person with peridural scarring, the dura and nerve roots are bound by fibrosis, and putting traction on the nerve roots and dura by back and limb movement produces pain. This pain is aggravated by the presence of inflammation at the surgical site. Research has shown that disc herniation activates the arachidonic acid cascade, resulting in the production of prostaglandins E1 and E2 and leukotriene B, substances that contribute to an inflammatory process that persists after discectomy. In an attempt to inhibit peridural fibrosis, methylprednisolone, polyethylene films, and fat grafts have been applied to the dura after discectomy. These experimental treatments have had limited success. Development of a therapy that reliably prevents peridural adhesive fibrosis will reduce the incidence of FBSS.