PubMed · 5962419
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1966. [Study session for otomicrosurgery].. https://pubmed.ncbi.nlm.nih.gov/5962419/
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Severe cases of Ménière's disease are successfully treated with ototoxic antibiotics. Gentamycin sulphate gives the best results. With the aid of a small syringe the drug is introduced into the external auditory canal 3-5 times per day. From there it is transported into the middle ear through a ventilating tube (Grommet) under slight pressure (Politzer bag). The liquid then penetrates the round and oval windows and influences inner-ear function. More than 90% of our patients in 25 years after therapy had no further attacks.
The author attempts to analyse the pathogenesis of the retraction pocket. Middle ear pressure, behaviour of both the tympanic membrane lamina propria and the stratified squamous epithelium are considered. Predisposing factors are presented. A conservative surgical treatment is suggested in cases of non-fixed retraction pockets; a radical surgical treatment is reserved for the fixed pockets. The management of mastoid cavities is discussed.