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PubMed · 597343

Role of complement in thrombogenesis. I. Complement-dependent coagulation in a model system.

Y H Abdulla·E McFarlene
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Abstract

Chondroitin sulphate was used to isolate from plasma a system that clotted with Russell's viper venom, brain extract and activated contact factors. Clotting appeared to depend on concomitant change in C4, C3 and C1s in the system. Brain extract additionally reacted with C9. Reconstitution of specifically defective plasmas suggested a specific role for each of these complement components in clotting.

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Antigen-Antibody ReactionsBlood CoagulationBlood PlateletsChondroitin SulfatesCoagulantsComplement C1 Inactivator ProteinsComplement C3Complement C4Complement C5Complement C9Complement System ProteinsHumansIn Vitro TechniquesJournal Article

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Y H Abdulla, E McFarlene. 1977. Role of complement in thrombogenesis. I. Complement-dependent coagulation in a model system.. https://doi.org/10.1016/0021-9150(77)90175-7

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