Mesangial cell dysfunction detected by accumulation of aggregated protein in rats with streptozotocin induced diabetes.

E N Wardle

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PubMed · 60145

Mesangial cell dysfunction detected by accumulation of aggregated protein in rats with streptozotocin induced diabetes.

E N Wardle

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Abstract

Diminished renal glomerular mesangial phagocytic function has been found in rats with streptozotocin induced diabetes. Similar impairment was produced by high dose cortisone and growth hormone, whereas oestrogen had a stimulant effect. The findings could be relevant to the understanding of human diabetic nephropathy.

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Animals Cortisone Diabetes Mellitus Fatty Acids Growth Hormone Kidney Glomerulus Mononuclear Phagocyte System Phagocytosis Protein Denaturation Rats Streptozocin gamma-Globulins Journal Article

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E N Wardle. 1975-10-20. Mesangial cell dysfunction detected by accumulation of aggregated protein in rats with streptozotocin induced diabetes.. https://pubmed.ncbi.nlm.nih.gov/60145/

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