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PubMed · 60518

Beta-lactamase-producing, penicillin-resistant gonococcus.

I Phillips
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Abstract

A gonococcus was isolated from the vagina of a woman with pelvic inflammatory disease. The organism was typical in all respects except that, unlike any previously described gonococcus, it produced a beta-lactamase that conferred resistance to penicillin, ampicillin, and cephaloridine. Among other antibiotics tested streptomycin was the only one to which the organism was resistant.

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AmpicillinCephaloridineCephalosporinsFemaleFuransGonorrheaHumansNeisseria gonorrhoeaePenicillin GPenicillin ResistancePenicillinasePenicillinsCase ReportsComparative StudyJournal Article

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BibTeXRIS

I Phillips. 1976-09-25. Beta-lactamase-producing, penicillin-resistant gonococcus.. https://doi.org/10.1016/s0140-6736(76)92466-1

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[Minimal effective dose of bacampicillin in urinary tract infections (author's transl)].

66 patients from a nephrological out-patient clinic in whom an ampicillin-sensitive pathogen had been demonstrated after suprapubic puncture, were divided into 3 randomised groups. The first group received 10, the second 20 and the third 30 tablets of 800 mg bacampicillin each. Tablets were given t.i.d. Due to randomising comparable groups were formed. When different criteria were used for assessment of success no advantages of long-term or disadvantages of short-term treatment were found. 10 tablets (possibly even less) are thus the minimal inhibitory dosage for the disease. Present experience suggests a short treatment with follow-up controls at short intervals and then a long-term reinfection prophylaxis.

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