Intestinal colonization and antibody response.

T Söderström; C C Brinton; L A Hanson; P Larsson; K G Rosén; A Sutton; R Schneerson

doi:10.1007/bf01640889

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Intestinal colonization and antibody response.

T Söderström·C C Brinton·L A Hanson·P Larsson·K G Rosén·A Sutton·R Schneerson

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Abstract

Rapid bacterial colonization of the gastrointestinal tract takes place immediately after birth. Only a few of the Escherichia coli strains colonizing the gut of healthy full-term neonates expressed MS pili. On the other hand, most E. coli strains isolated carried MR pili resembling the P-fimbriae which are a known virulence factor for pyelonephritogenic E. coli. The presence of serum antibodies against pili and K antigens of E. coli after vaccination did not influence the capacity of E. coli to colonize and persist in the intestine of experimental animals.

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Animals Antibodies, Bacterial Antigens Antigens, Bacterial Antigens, Surface Colon Digestive System Escherichia coli Feces Fimbriae, Bacterial Humans Infant, Newborn Intestine, Small Mice Nasopharynx Vaccination Journal Article Research Support, Non-U.S. Gov't

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T Söderström, C C Brinton, L A Hanson, P Larsson, K G Rosén, A Sutton, R Schneerson. Intestinal colonization and antibody response.. https://doi.org/10.1007/bf01640889

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