Decrease in N-acetyl-L-aspartic acid in brain of myodystrophic mice.

F Marcucci; L Colombo; G De Ponte; E Mussini

doi:10.1111/j.1471-4159.1984.tb05412.x

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Decrease in N-acetyl-L-aspartic acid in brain of myodystrophic mice.

F Marcucci·L Colombo·G De Ponte·E Mussini

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Abstract

Brain tissue from myodystrophic mice (male 129/ReJ-dy and female 129 B6F1/J-dy) was examined to determine whether CNS abnormalities accompany the known muscular defects. Brain N-acetyl-L-aspartate, aspartate, and glutamate were significantly lower than in brain from control mice. These amino acids are only slightly reduced in brains of female dystrophic mice.

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Animals Aspartic Acid Brain Female Glutamates Glutamic Acid Male Mice Mice, Mutant Strains Muscular Dystrophy, Animal Sex Factors Journal Article Research Support, Non-U.S. Gov't

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F Marcucci, L Colombo, G De Ponte, E Mussini. 1984. Decrease in N-acetyl-L-aspartic acid in brain of myodystrophic mice.. https://doi.org/10.1111/j.1471-4159.1984.tb05412.x

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