[Palatal myoclonus associated with a decrease in 5-hydroxy-indole acetic acid in cerebrospinal fluid and responding to clonazepam].

S Gauthier; S N Young; D W Baxter

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PubMed · 6164459

[Palatal myoclonus associated with a decrease in 5-hydroxy-indole acetic acid in cerebrospinal fluid and responding to clonazepam].

S Gauthier·S N Young·D W Baxter

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Abstract

A patient representing with palatal myoclonus was diagnosed as suffering from possible multiple sclerosis. A reduction of cerebrospinal 5-hydroxy-indole-acetic acid suggested a decreased central serotonergic turnover. A therapeutic trial with clonazepam, a serotonergic agonist, improved the myoclonus symptomatically. The possible involvement of serotonergic inhibitory systems in the expression of palatal myoclonus is discussed.

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Benzodiazepinones Clonazepam Female Humans Hydroxyindoleacetic Acid Middle Aged Multiple Sclerosis Muscles Myoclonus Palatal Muscles Tryptophan Case Reports English Abstract Journal Article

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S Gauthier, S N Young, D W Baxter. 1981. [Palatal myoclonus associated with a decrease in 5-hydroxy-indole acetic acid in cerebrospinal fluid and responding to clonazepam].. https://pubmed.ncbi.nlm.nih.gov/6164459/

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