Reserpinization: effects on parotid gland function.

E Watson; F Dowd; K Jacobson; H Horwitz

doi:10.1177/00220345840630021401

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Reserpinization: effects on parotid gland function.

E Watson·F Dowd·K Jacobson·H Horwitz

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Abstract

Chronic reserpinization of mice and rabbits affected parotid gland function; cholinergic and beta-adrenergic-stimulated amylase release were significantly reduced, and cyclic-AMP and cyclic-GMP levels were significantly elevated above control-stimulated levels. Amylase released by dibutyryl-c-AMP was also reduced, suggesting a defect in stimulus-secretion coupling subsequent to c-AMP formation.

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Amylases Animals Carbachol Cyclic AMP Cyclic GMP Isoproterenol Male Mice Mice, Inbred Strains Parotid Gland Rabbits Receptors, Adrenergic, beta Receptors, Cholinergic Reserpine Journal Article Research Support, U.S. Gov't, P.H.S.

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E Watson, F Dowd, K Jacobson, H Horwitz. 1984. Reserpinization: effects on parotid gland function.. https://doi.org/10.1177/00220345840630021401

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