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Abnormal keratohyalin-like forms in leukoedema.

C W Van Wyk·S C Ambrosio·P C van der Vyver
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Abstract

Electron microscopic, histochemical and light-microscopic studies were carried out on biopsy specimens of 12 cases of leukoedema and on the desquamated epithelial cells of a further 50 examples. For comparison, similar observations were made of 4 examples of healthy cheek mucosa and 29 cases of a variety of pathological conditions of the oral mucosa. Only in leukoedema were a series of structures encountered which consisted of an aggregation of ribosomes and electron dense masses, or a network of electron-dense material, or an electron-dense network with a central dense core or a solid body with a few central cavities. Histochemical stains and RNA extraction studies showed that they are probably abnormal forms of keratohyalin granules and that ribosomes is an important component of their composition.

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Cytoplasmic GranulesHumansHyalinKeratinsLeukoedema, OralMicroscopy, Electron, ScanningMouth DiseasesMouth MucosaRNA, RibosomalRibosomesComparative StudyJournal Article

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BibTeXRIS

C W Van Wyk, S C Ambrosio, P C van der Vyver. 1984. Abnormal keratohyalin-like forms in leukoedema.. https://doi.org/10.1111/j.1600-0714.1984.tb01425.x

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