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Immunoreactive substance P in the tubero-hypophyseal system of the rat: selective decrease in the neural lobe after dehydration and sodium loading.

M Holzbauer·J Donnerer·P Holzer·W Schluet·F Lembeck·D F Sharman
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Abstract

In the tubero-hypophyseal system of the rat the approximate concentrations of immunoreactive substance P (I-SP), expressed as fmol/mg tissue, were 100 in the medial basal hypothalamus (MBH), 20 in the anterior lobe (AL), 20 in the neural lobe (NL) and 4 in the intermediate lobe of the hypophysis. These values were not altered by treatment with capsaicin on day 2 after birth. In rats in which the secretion of neurohormones from the NL was increased by dehydration followed by sodium loading there was a fall by 70% in the I-SP concentration of the NL; no change occurred in the AL or the MBH.

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AnimalsCapsaicinDehydrationHypothalamo-Hypophyseal SystemMalePituitary GlandRatsRats, Inbred StrainsSodiumSubstance PTissue DistributionJournal ArticleResearch Support, Non-U.S. Gov't

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M Holzbauer, J Donnerer, P Holzer, W Schluet, F Lembeck, D F Sharman. 1984-06-01. Immunoreactive substance P in the tubero-hypophyseal system of the rat: selective decrease in the neural lobe after dehydration and sodium loading.. https://doi.org/10.1016/0304-3940(84)90380-x

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