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PubMed · 6233973

High mobility group proteins HMG1 and HMG2 do not decrease the melting temperature of DNA.

L N Marekov·B G Beltchev·L Pivec
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Abstract

High mobility group proteins 1 and 2 isolated in non-denaturing conditions cannot decrease the temperature of denaturation of DNA. When they are isolated or treated with tricloroacetic acid a hyperchromic peak below the melting temperature of free DNA appears in agreement with previous data ( Javaherian et al. (1979) Nucl . Acids Res. 6, 3569-3580). We show that this is due to light scattering of aggregated protein at submelting temperatures and not to melting of DNA.

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AnimalsCattleChromosomal Proteins, Non-HistoneDNAHigh Mobility Group ProteinsNucleic Acid DenaturationThermodynamicsJournal Article

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L N Marekov, B G Beltchev, L Pivec. 1984-05-16. High mobility group proteins HMG1 and HMG2 do not decrease the melting temperature of DNA.. https://doi.org/10.1016/s0006-291x(84)80175-8

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