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PubMed · 62411

Plasmin inactivation in plasma.

E M Haselager·T M Goote·J Vreeken
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Abstract

Inhibition and inactivation of plasmin is ascribed to alpha2-macroglobulin, alpha1-antitrypsin and c1-esterase inhibitor. In an "overall" inactivation test of plasmin in plasma, which comes perhaps closest to rapid inactivation of plasmin in the circulating blood, we only found a correlation between the immunological concentration of alpha2-macroglobulin and the plasmin-inactivating capacity of the plasma, but no correlation with the immunological concentration of the other inhibitors mentioned. Therefore, alpha2-macroglobulin seems to be the most important plasmin inhibitor in relation to thrombosis.

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Blood Coagulation TestsEnzyme InhibitorsEsterasesFibrinolysinHumansalpha 1-Antitrypsinalpha-MacroglobulinsJournal Article

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E M Haselager, T M Goote, J Vreeken. 1976-06-30. Plasmin inactivation in plasma.. https://pubmed.ncbi.nlm.nih.gov/62411/

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