A mouse alpha-globin-related pseudogene lacking intervening sequences.

E F Vanin; G I Goldberg; P W Tucker; O Smithies

doi:10.1038/286222a0

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A mouse alpha-globin-related pseudogene lacking intervening sequences.

E F Vanin·G I Goldberg·P W Tucker·O Smithies

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Abstract

A mouse alpha-globin-related pseudogene (psi alpha 30.5) completely lacks intervening sequences, and could not code for a functional globin poypeptide because of frameshifts. The widespread occurrence of globin pseudogenes in other species suggests that they are not 'dead' genes but may be important in controlling globin expression.

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Animals Base Sequence Biological Evolution DNA Restriction Enzymes Genes Globins Mice Mice, Inbred BALB C Transcription, Genetic Journal Article Research Support, U.S. Gov't, P.H.S.

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E F Vanin, G I Goldberg, P W Tucker, O Smithies. 1980-07-17. A mouse alpha-globin-related pseudogene lacking intervening sequences.. https://doi.org/10.1038/286222a0

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