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PubMed · 6255377

Selectivity in synaptic changes caudal to acute spinal cord transection.

T C Cope·S G Nelson·L M Mendell
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Abstract

The amplitude of monosynaptic EPSPs produced by the action of single semitendinosus (ST) Ia afferent fibers in ST motoneurons display little or no increase in amplitude within hours of a spinal cord transection performed at the thirteenth thoracic segment. This finding is in marked contrast to results obtained at the medial gastrocnemius (MG) Ia fiber-motoneuron synapse, where EPSPs have been shown to be enlarged, even in preparations with normal ST EPSPs. The increase in EPSP amplitude reported previously at the MG Ia-motoneurons synapse is selective and therefore is probably not a direct consequence of injury to the isolated segment of the spinal cord.

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Acute DiseaseAnimalsCatsCordotomyMembrane PotentialsMotor NeuronsSpinal CordSpinal Cord InjuriesSynapsesSynaptic TransmissionJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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T C Cope, S G Nelson, L M Mendell. 1980. Selectivity in synaptic changes caudal to acute spinal cord transection.. https://doi.org/10.1016/0304-3940(80)90162-7

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