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PubMed · 6262533

Nucleotide sequence changes in polyoma ts-a mutants: correlation with protein structure.

P L Deininger·P LaPorte·T Friedmann
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Abstract

The mutations in three polyoma ts-a mutants have been determined. Two mutants, ts-25 and ts-52, have different single-base changes at the same position (2883) in the early region corresponding to a conserved glycine residue very near the C-terminus of the polyoma large T antigen. Mutant ts-48 has a single-base change at position 2341, as well as a second change at position 1228, in the region of large T antigen shared with medium T antigen.

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Amino Acid SequenceAntigens, NeoplasmAntigens, ViralBase SequenceGenes, ViralMutationPolyomavirusTemperatureJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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P L Deininger, P LaPorte, T Friedmann. 1981. Nucleotide sequence changes in polyoma ts-a mutants: correlation with protein structure.. https://doi.org/10.1128/jvi.37.3.871-875.1981

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