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PubMed · 6291665

Membrane changes during viral infection.

C A Pasternak·M A Gray·K J Micklem
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Abstract

The effect of viruses on the surface membrane of susceptible cells during the entry and exit process has been studied. Haemolytic paramyxoviruses induce a non-specific leakage to low-molecular-weight compounds during entry; other viruses do not show this effect. During exit, no such changes occur with any virus so far studied: some viruses are released without any obvious change at all in surface membrane function; in other cases, uptake of some nutrients is altered and there is a fall in membrane potential. These results do not support the hypothesis that a generalized membrane leakiness is a prerequisite for the synthesis and release of virus particles.

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AnimalsCell LineCell MembraneCell Transformation, ViralHumansMeasles virusMembrane PotentialsOrthomyxoviridaeParainfluenza Virus 1, HumanPotassiumRNA VirusesSemliki forest virusSpecies SpecificityVesicular stomatitis Indiana virusJournal ArticleResearch Support, Non-U.S. Gov't

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C A Pasternak, M A Gray, K J Micklem. 1982. Membrane changes during viral infection.. https://doi.org/10.1007/bf01314224

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