Purine enzymes and immune function.

R W Watts

doi:10.1016/s0009-9120(83)94398-9

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Purine enzymes and immune function.

R W Watts

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Abstract

The term immune function is taken to mean the process by which lymphocytes respond to an antigenic challenge. This response involves cell division and differentiation, which depend on purine nucleotides. The present state of knowledge relating events at the cell surface to the necessarily increased rate of purine de novo synthesis, and the modulation of purine nucleotide interconversions through the mediation of putative intracellular messengers, is reviewed. These physiological processes are related, where possible, to some genetic and pharmacologically induced perturbations of the systems involved.

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5'-Nucleotidase Cell Membrane Enzymes Humans Immunologic Deficiency Syndromes Lymphocyte Activation Lymphocytes Nucleotidases Purine Nucleosides Purine Nucleotides Purines Comparative Study Journal Article Review

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R W Watts. 1983. Purine enzymes and immune function.. https://doi.org/10.1016/s0009-9120(83)94398-9

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