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Identifying superoxide-sensitive progenitor cells in mouse bone marrow.

W S Chelack·A Petkau
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Abstract

Macrophage progenitor cells in bone marrow, that develop into attached colonies in liquid culture medium, contain a fraction of cells sensitive to photochemically generated superoxide radicals. This fraction varies from one animal to another. Populations of cells containing the superoxide-sensitive fraction show a greater sensitivity to X-rays than do populations in which this fraction has been photochemically inactivated. The change in radiosensitivity was proportional to the superoxide-sensitive fraction.

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AnimalsBone Marrow CellsCell SurvivalDose-Response Relationship, RadiationFemaleLightMiceRadiation ToleranceStem CellsSuperoxidesJournal Article

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W S Chelack, A Petkau. 1983. Identifying superoxide-sensitive progenitor cells in mouse bone marrow.. https://doi.org/10.1080/09553008314551531

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