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PubMed · 63343

The effects of BCG on both cellular and humoral immunity during the early response to a hapten carrier complex.

P J Neveu
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Abstract

Cell-mediated reactions to the carrier and antibody-mediated reactions to hapten and carrier were studied in guinea-pigs treated with a single i.v. injection of BCG at different intervals of time before immunization with two different doses of a hapten-carrier complex. The results clearly show that BCG-induced delayed hypersensitivity reactions to the carrier and decreased antibody synthesis to the hapten. It is proposed that BCG acts on a dispatcher cell which controls both cellular and humoral immunity.

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AnaphylaxisAnimalsAntibody FormationAntigen-Antibody ReactionsBCG VaccineDinitrophenolsGuinea PigsHaptensHypersensitivity, DelayedImmunity, CellularImmunizationMycobacterium bovisSkin TestsTime Factorsgamma-GlobulinsJournal Article

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P J Neveu. 1976. The effects of BCG on both cellular and humoral immunity during the early response to a hapten carrier complex.. https://pubmed.ncbi.nlm.nih.gov/63343/

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