Hapten-antibody interactions as determined by fluorescence polarization.

In order to better understand the relationship between IgA and IgG antibodies to Epstein-Barr virus (EBV) in nasopharyngeal carcinoma (NPC), we analyzed 230 NPC sera but also a series of sera from patients with other carcinomas selected for their high EBV/IgG antibody titres. We were surprised to find that 21 out of 46 sera from bronchopulmonary carcinomas (BPC) and 6 out of 7 carcinomas of nasal fossae were IgA anti-VCA positive, and 9 BPC sera and 5 nasal fossae sera were also positive for IgA and anti-EA. Bronchial undifferentiated small-cell carcinomas may represent a particular group associated with high EBV profile.

Antibody Specificity↗

PubMed1979

[Gamma globulin in secondary antibody deficiency syndrome].

12 patients with secondary antibody deficiency syndrome received a new gammaglobulin compound intravenously (lyoph. SRK Sandoz). The drug was given in a 3% NaCl-solution once to four times. At the end of the infusion of 6 g gammaglobulin and after one week, serum levels were significantly higher. Gammaglobulin intravenously was well tolerated in all cases. Severe infections during the period of treatment were not observed.

Antibody Specificity↗

PubMed1979

Measurement of pregnancy associated plasma protein A (PAPP-A).

A method is described for measuring pregnancy associated plasma protein A (PAPP-A) in the maternal circulation during the 3rd trimester of pregnancy. The method used is a modification of Laurell's electroimmunodiffusion technique.

Antibody Specificity↗