Nuclear RNA-protein interactions and messenger RNA processing.

T Pederson

doi:10.1083/jcb.97.5.1321

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Nuclear RNA-protein interactions and messenger RNA processing.

T Pederson

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Abstract

Eucaryotic messenger RNA precursors are processed in nuclear ribonucleoprotein particles (hnRNP). Here recent work on the structure of hnRNP is reviewed, with emphasis on function. Detailed analysis of a specific case, the altered assembly of hnRNP in heat-shocked Drosophila and mammalian cells, leads to a general hypothesis linking hnRNP structure and messenger RNA processing.

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Animals Base Sequence Heterogeneous-Nuclear Ribonucleoproteins Hot Temperature Models, Genetic Molecular Weight Nucleic Acid Conformation RNA, Messenger Ribonucleoproteins Transcription, Genetic Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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T Pederson. 1983. Nuclear RNA-protein interactions and messenger RNA processing.. https://doi.org/10.1083/jcb.97.5.1321

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