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PubMed · 6381989

[Does the hematopoietic stem cell exist?].

I L Chertkov
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Abstract

The hypothesis concerning the existence of a self-maintaining, i. e. "immortal" hemopoietic stem cell has no conclusive evidence. The data demonstrating the existence of hemopoietic cells with very high proliferative potentials, which are formed only during embryogenesis are discussed. Clonal expansion of these cells can support hemopoiesis during the entire life of the adult organism.

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AnimalsCell DifferentiationCell DivisionCell SurvivalCells, CulturedClone CellsColony-Forming Units AssayDosage Compensation, GeneticFemaleGenetic MarkersGlucosephosphate DehydrogenaseHematopoietic Stem CellsHumansIsoenzymesMiceModels, BiologicalPyruvate KinaseSpleenEnglish AbstractJournal ArticleReview

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I L Chertkov. [Does the hematopoietic stem cell exist?].. https://pubmed.ncbi.nlm.nih.gov/6381989/

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