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Isotherm mapping in hyperthermia using subtraction X-ray computed tomography.

S M Bentzen·J Overgaard·J Jørgensen
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Abstract

The prospects for the use of X-ray computed tomography (CT) for isotherm mapping were investigated. The spatial distribution of CT changes was obtained by digital subtraction of images taken before and during heating of a 200 mm diameter cylindrical 4% agar phantom. Due to a rather unfavourable signal-to-noise ratio, the noise level in the resulting image had to be reduced by low-pass filtering using the 2-dimensional Fast Fourier Transform followed by spatial averaging. The resulting isotherms showed a resolution of 0.5 degree C at a spatial resolution of 4.2 mm. Isotherms so obtained are presented and the possibility of using the method in clinical hyperthermia is discussed.

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HumansHyperthermia, InducedModels, StructuralSubtraction TechniqueTomography, X-Ray ComputedJournal ArticleResearch Support, Non-U.S. Gov't

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S M Bentzen, J Overgaard, J Jørgensen. 1984. Isotherm mapping in hyperthermia using subtraction X-ray computed tomography.. https://doi.org/10.1016/s0167-8140(84)80066-3

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