Dissimilar rates in molecular evolution.

M A Soto; J Tohá

doi:10.1007/bf00933714

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PubMed · 6462698

Dissimilar rates in molecular evolution.

M A Soto·J Tohá

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Abstract

In this work we present an evolutionary tree based on the differences in the physico-chemical properties involved in amino acid substitutions, instead of considering, for its construction, only the number of changes between species. Phylogenetic trees were constructed from the differences in bulkiness, refractivity index, hydrophobicity, polarity and optical rotation of 9 vertebrate calcitonins. A correlation of the form y = a xb was found between the number of changes (x) and the differences in any given physico-chemical property (y). This correlation implies that the evolutionary time can not be evaluated directly from the number of changes between species.

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Amino Acid Sequence Animals Biological Evolution Calcitonin Humans Models, Genetic Optical Rotation Phylogeny Protein Conformation Species Specificity Time Factors Comparative Study Journal Article Research Support, Non-U.S. Gov't

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M A Soto, J Tohá. 1984. Dissimilar rates in molecular evolution.. https://doi.org/10.1007/bf00933714

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