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PubMed · 6504980

Cyclodextrin-stabilized volatile substances for inhalation therapy.

M Gál-Füzy·L Szente·J Szejtli·J Harangi
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Abstract

Diapulmon (Chinoin) which comprise camphor, 1-menthol, eucalyptus oil and quinine dissolved in sunflower oil (Oleum helianthi) is marketed in ampoules of 2 ml but utilized almost exclusively for inhalation therapy. Complexing the active ingredients of Diapulmon with beta-cyclodextrin (beta-CD) a stable non hygroscopic microcrystalline substance is obtained. When this powder sprinkled on hot water, the included volatile compounds are gradually released and the desired pharmacological effect can be brought about.

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CamphorChromatography, GasCyclodextrinsDextrinsDrug CombinationsDrug StabilityExcipientsMentholOils, VolatileQuinineRespiratory TherapyStarchJournal Article

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BibTeXRIS

M Gál-Füzy, L Szente, J Szejtli, J Harangi. 1984. Cyclodextrin-stabilized volatile substances for inhalation therapy.. https://pubmed.ncbi.nlm.nih.gov/6504980/

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