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PubMed · 6508448

Warfarin interaction with erythromycin.

R I Sato·D R Gray·S E Brown
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Abstract

The drug interaction between warfarin and erythromycin is not well known. We report a case in which erythromycin was observed to markedly potentiate warfarin anticoagulation, resulting in hemorrhage in a patient treated for Legionella pneumonia. The morbidity of this drug interaction is enhanced in elderly patients who have infection accompanied by anorexia and/or fever and who are receiving intravenous erythromycin. The well-documented, temporal relationship established erythromycin as the interacting drug.

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Drug InteractionsErythromycinHemoptysisHumansLegionnaires' DiseaseMaleMiddle AgedWarfarinCase ReportsJournal Article

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R I Sato, D R Gray, S E Brown. 1984. Warfarin interaction with erythromycin.. https://pubmed.ncbi.nlm.nih.gov/6508448/

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